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RHO | Methylated B-Complex

RHO | Methylated B-Complex

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Methylated B vitamins (methylfolate, methylcobalamin) Clean

What it is: Active forms of folate and vitamin B12.

Why it's used: Used as the B-vitamin source in supplements.

Our take: Clean. A go-to for us.

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Monk fruit extract Clean

What it is: A zero-calorie sweetener extracted from monk fruit, a small melon.

Why it's used: Adds sweetness without sugar, often alongside stevia or allulose.

Our take: Clean. A go-to for us.

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Preservatives (sodium benzoate, potassium sorbate) Okay

What it is: Common preservatives.

Why it's used: Keep drinks and foods shelf-stable.

Our take: Okay. We like it when a product doesn’t need them.

Why it's flagged: FDA has noted that sodium benzoate and vitamin C together can form trace amounts of benzene in some drinks, especially with heat or light. FDA’s testing found most beverages at very low levels. Source

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Sunflower lecithin Clean

What it is: An emulsifier made from sunflower seeds.

Why it's used: Helps powders mix and keeps ingredients blended.

Our take: Clean. Soy-free.

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Tiers apply to food, drinks and supplements. Ingredient glossary →

Description

Energy, Stress & Cellular Vitality

Liposomal Methylated B-Complex delivers a full spectrum of essential B vitamins in their biologically active, methylated, or coenzyme forms in an advanced liposomal delivery system designed for enhanced absorption.*

B vitamins play a foundational role in energy production, nervous system health, stress response, and metabolic function. By supporting these core pathways, this comprehensive B-complex promotes cellular energy, cognitive function, cardiovascular health, and overall vitality.*

Guava Flavor.

Rho uses liposomal delivery — nutrients are enclosed in tiny phosphatidylcholine-based liposomes that help protect them through digestion and support absorption.*

FAQs

What does “methylated” mean?

Methylated B vitamins are the biologically active forms your body can use immediately. Unlike synthetic versions, they do not require additional conversion steps, supporting more efficient utilization.*

Why are active forms like P5P, methylfolate, and methyl B12 important?

These forms are already in the state your body uses for energy production, neurotransmitter synthesis, methylation, and metabolic processes, helping bypass common conversion limitations.*

How long does one bottle last?

Each bottle contains 30 servings. When taken daily as directed, it will last 30 days.

Why liposomal? What does liposomal delivery do?

Liposomal delivery encapsulates nutrients inside phospholipid spheres that help protect them during digestion and support efficient absorption, allowing nutrients to be delivered where they are needed most—inside the cell.*

Is this formula helpful for people with MTHFR variations?

Genetic variations such as MTHFR can reduce the ability to convert standard forms of folate and B12 into their active forms. Because this formula provides L-methylfolate and methylcobalamin, it bypasses several conversion steps.* We recommend consulting a licensed healthcare provider for personal guidance.

What benefits can I expect from taking this?

Benefits vary by individual and depend on overall health, nutritional status, and consistency of use. However, this formula supports:

  • Cellular energy & metabolism*
  • Nervous system & cognitive function*
  • Stress response & adrenal support*
  • Healthy methylation*
  • Cardiovascular & homocysteine support*

Are there side effects?

Methylated B vitamins are generally well tolerated. Some individuals may notice increased energy or changes in sleep or mood when starting. If sensitive to methyl donors, consider starting with a smaller amount and increasing as tolerated.

Can I take this with my other supplements?

Yes. This product pairs well with magnesium, glutathione, vitamin C, and other daily essentials. Consult your healthcare provider if you take medications or have a medical condition.

Ingredients

Serving Size: Just Over One Teaspoon (6 mL)

Servings Per Bottle: 30

Thiamin (as Thiamin HCl)...10 mg (833% DV)Riboflavin...5 mg (385% DV)Niacin (as Niacinamide)...20 mg NE (125% DV)Vitamin B6 (as Pyridoxal-5-Phosphate)...10 mg (588% DV)Folate (as L-5-Methyltetrahydrofolate)...2.5 mg DFE (625% DV)Vitamin B12 (as Methylcobalamin)...300 mcg (12,500% DV)Pantothenic Acid (as D-Calcium Pantothenate)...20 mg (400% DV)

Other Ingredients: Purified Water, Monk Fruit Juice (Siraitia grosvenorii), Tangerine Flavor, Non-GMO Sunflower Lecithin, Mango Flavor, Glycerin, Potassium Sorbate

Always refer to the product label for the most current ingredient information.

Benefits

  • Supports cellular energy production*
  • Promotes healthy nervous system function*
  • Active B vitamins for methylation support*
  • Supports healthy stress response and homocysteine metabolism*

Energy Production & Metabolism

B vitamins are essential cofactors in mitochondrial energy production and the metabolism of carbohydrates, fats, and proteins. This formula supports efficient energy production and metabolic function at the cellular level.*

Nervous System & Cognitive Function

Thiamin (B1), riboflavin (B2), vitamin B6, folate (B9), and vitamin B12 support healthy nervous system structure and function and play key roles in neurotransmitter synthesis involved in focus, mental clarity, mood, sleep, and cognitive performance.*

Stress Response & Adrenal Support

Pantothenic acid (B5), vitamin B6 (P5P), and vitamin B12 support the body’s response to physical and mental stress by supporting adrenal function and balanced neurotransmitter activity.*

Methylation & Cellular Health

Folate (as L-5-Methyltetrahydrofolate) and vitamin B12 (as methylcobalamin) support healthy methylation processes involved in DNA synthesis, detoxification pathways, neurotransmitter production, and homocysteine metabolism.*

Cardiovascular & Red Blood Cell Support

B vitamins support healthy homocysteine metabolism and red blood cell formation, both essential for cardiovascular health and oxygen delivery throughout the body.*

Features

  • Liposomal delivery for absorption support
  • Guava Flavor
  • Third-party tested
  • Refrigeration optional — Rho suggests refrigerating for the best taste

Directions & Warnings

Directions:

How do I take Liposomal Methylated B-Complex?

Take 6 mL (just over one teaspoon) per day, or as recommended by your healthcare practitioner. You can take it directly from the spoon or mix it into a cold beverage.

Does it need to be refrigerated?

Before opening: Store in a cool, dry place. After opening: Refrigeration is not required but is recommended for taste and freshness. Use within 45 days of opening.

Warnings: Keep out of reach of children. If you are pregnant, nursing, taking any medications, or have a medical condition, consult your healthcare provider before use.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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