Thorne | Methyl-Guard Plus
Thorne | Methyl-Guard Plus
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What's Inside
What's Inside
Methylated B vitamins (methylfolate, methylcobalamin) Clean
What it is: Active forms of folate and vitamin B12.
Why it's used: Used as the B-vitamin source in supplements.
Our take: Clean. A go-to for us.
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Description
Description
Methyl-Guard Plus provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.*
Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.
Thorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*
Why is methylation important?
Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:
- Cardiovascular health
- Cellular energy production
- Fat metabolism
- Neurological function
- DNA production
- Liver detoxification processes
- Eye health
- Histamine balance
Who can benefit from Thorne Methyl-Guard Plus
- Individuals with variations to MTHFR and other genes that adversely affect methylation*
- Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health*
- Women seeking support for estrogen metabolism and bone health*
- Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*
- Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables
Ingredients
Ingredients
Amount per serving:
- Betaine Anhydrous (Trimethylglycine) – 1.8 g
- Folate (L-5-MTHF) – 5 mg DFE
- Vitamin B12 (as Methylcobalamin) – 3 mg
- Vitamin B6 (as Pyridoxal 5'-Phosphate) – 45 mg
- Vitamin B2 (Riboflavin 5'-Phosphate Sodium) – 90 mg
Other ingredients: Calcium (Citrate), Calcium Laurate, Hypromellose (derived from cellulose) capsule
Always refer to the product label for the most current ingredient information.
Benefits
Benefits
Support cellular energy production, heart health, brain function, and mood with nutrients that optimize methylation*
Benefits of Thorne Methyl-Guard Plus
- Nutritional support for individuals who have MTHFR gene variations*
- Enhanced cellular energy production fights occasional fatigue*
- Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*
- Promotes fat metabolism and lean body composition*
- Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*
- Promotes liver detoxification of many substances, including hormones like estrogen*
Supports: Energy, Heart & Vessels, Hormone Support, Men's Health, Methylation
Features
Features
- Betaine, also known as trimethylglycine, is a superior methyl donor
- The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*
- Active forms of vitamins B2 and B6 – key cofactors in methylation processes
- B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*
- Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard
This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.
- Derived From Natural Flavors
- Derived From Natural Colors
- Gluten Free
- Dairy Free
- Soy Free
- Form: Capsule
- Size: 90 capsules
Directions & Warnings
Directions & Warnings
Directions: Take 1-3 capsules daily or as recommended by your health-care practitioner.
Warnings:
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health-care practitioner before using this product.
INTERACTIONS
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
Keep out of reach of children.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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